scleromyxedema
نویسندگان
چکیده
scleromyxedema is a rare, chronic, progressive, fibromucinous disorder of unknown etiology, characterized by lichenoid waxy papules and firm induration of skin of trunk, face, forearm and hands; fibroblast proliferation and mucin deposition in the upper dermis. cutaneous involvement is characteristic but there are several associated systemic manifestations: we observed a case of scleromyxedema with multiple systemic manifestations including endocrinopathy and hypothyroidism. scleromyxedema is a multisystem disorder associated with multiple organ involvement including liver, muscle, kidney and could be associated with endocrinopathies including hypothyroidism.
منابع مشابه
Scleromyxedema with subclinical myositis.
A 49-year-old farmer presented with papules on the face, arms, chest and back associated with sclerosis. Histopathology and PAS stain confirmed the clinical diagnosis of scleromyxedema. He also had elevated CPK levels due to myopathy. Screening for internal malignancy was negative.
متن کاملScleromyxedema: possible association with seminoma.
Although scleromyxedema has been associated with neoplasm in rare instances, the literature showed no evidence of association with seminoma. We report a 43-year-old man who presented with a scleromyxedema and relapsed seminoma. The skin lesions of scleromyxedema cleared completely on treatment of seminoma with chemotherapy.
متن کاملScleromyxedema diagnosis following unexplained encephalopathy.
CORRESPONDENCE Scleromyxedema diagnosis following unexplained encephalopathy Scleromyxedema is a rare idiopathic disorder, characterized by papules in a thickened mucinous dermis, with fi bro-blastic proliferation and monoclonal paraproteinemia [1, 2]. Typically, scleromyxedema affects middle-aged men, has a chronic progressive course and frequently pre sents extracutaneous complications that g...
متن کاملTreatment of scleromyxedema with IVIg
Results An 18 year old male presented with a rash of three weeks duration. Soon after the rash appeared, he developed pain and swelling of the right hand, as well as numbness and tingling of the right forearm. A recreational weight lifter, he noticed progressively decreasing stamina and amount of weight that he could lift. Swelling of the eyelids and bridge of nose prompted treatment for an all...
متن کاملManaging scleromyxedema with intravenous immunoglobulin: acute worsening of scleromyxedema with biclonal gammopathy.
Scleromyxedema is a rare chronic cutaneous mucinosis usually associated with a monoclonal gammopathy and underlying systemic disease. The etiology of the disease is not known. There are no standard treatments and response to various therapeutic modalities varies. We report a case of refractory scleromyxedema in a 63-year-old man with a biclonal IgG and IgM λ-gammopathy. The patient was successf...
متن کاملThalidomide as a potential treatment for scleromyxedema.
A 39-year-old African American woman was referred in April 1995 with a 1-year history of skin thickening. The process began on her hands and progressed to involve her arms, face, neck, shoulders, chest, and proximal extremities. Her only systemic complaints were limited mobility of her joints, particularly her hands and wrists. Physical examination findings revealed leonine facies. The skin of ...
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عنوان ژورنال:
acta medica iranicaجلد ۳۴، شماره ۳-۴، صفحات ۹۵-۱۰۰
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